Amifostine improves the antileukemic therapeutic index of mafosfamide: implications for bone marrow purging
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چکیده
منابع مشابه
Amifostine improves the antileukemic therapeutic index of mafosfamide: implications for bone marrow purging.
One of the principal challenges of cancer chemotherapy is the relative inability of most anticancer drugs to distinguish between normal and neoplastic tissues. Consequently, a broad range of toxicities are experienced by patients, especially myelosuppression. Amifostine, a phosphorylated aminothiol, increases the selectivity of specific anticancer drugs for neoplastic cells by protecting normal...
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ژورنال
عنوان ژورنال: Blood
سال: 1995
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood.v86.7.2849.2849